The Bills are 1-1 on the road this year and the Giants are 1-1 at home this season, so the home field is not that big of an advantage for the Giants.  The Bills are going to try to keep rolling while the Giants are going to try to get back on track after losing a stunner at home to the Seahawks last weekend.  Here is a look at the matchups in this game:

When the Bills have the ball:  Something has to give this weekend as Ryan Fitzpatrick has only been sacked 4 times so far this year, while the Giants already have 18 sacks on defense.  If the Bills can protect Fitzpatrick, he’s going to have success throwing against the Giants as they are giving up 251.2 yards passing per game so far this year.  The Bills are also likely going to give the ball a lot to RB Fred Jackson as the Giants are giving up 122.2 yards rushing per game and 4.2 yards per carry so far this year.

When the Giants have the ball:  The Bills are giving up 421.8 yards per game so far this year, so the Giants are apt to get their fair share of yards this Sunday in New Jersey.  The bad thing for the Bills this weekend is that they only have five sacks so far this year, so Eli Manning is going to have a lot of time to throw the ball.  WRs Victor Cruz, Hakeem Nicks and Mario Manningham are going to give the Bills’ secondary fits in this game.  Still, the Bills do have 12 pickoffs so far this year and Eli Manning has been known to take chances down the field with the ball.  Ahmad Bradshaw has struggled so far this year, but the Bills’ D is allowing 138.4 yards rushing and 5.5 yards per carry, so he might awaken this weekend.

PREDICTION:  GIANTS 31, BILLS 27

The Buffalo Bills are going to try to get back on the right track this Sunday at home against the Eagles.  The Bills are 2-0 at home, having outscored the Patriots and Raiders by a combined score of 72-66.  Look for another high scoring game this Sunday.  Here is a look at the matchups in this game:

When the Bills have the ball:  The Bills are going to try to control the clock in this game.  The Eagles are giving up 139.5 yards rushing per game and 5.3 yards per carry.  So it makes perfect sense to unleash Fred Jackson on the Eagles’ front seven as many times as he can handle toting the rock.  Look for C.J. Spiller to get some carries and for Brad Smith to be on the field more, looking to make some trick plays.  The Eagles already have 15 sacks this year and DE Jason Babin already has 7 of them on his own!  The Bills have only given up 3 sacks this year and they are going to need to give Ryan Fitzpatrick time to throw the ball if he’s going to have success.  The Eagles’ secondary is much better than they have played so far this year, but the Bills still need to attack them down the field with WRs Steve Johnson, David Nelson and Donald Jones.  Look for TE Scott Chandler to get more looks than usual in this game for the Bills as Fitzpatrick might have to get rid of the ball quickly due to the Eagles’ pass rush.

When the Eagles have the ball:  The Bills’ D doesn’t match up too well with the Eagles’ offense.  Michael Vick is at his best when he can roll out and decide whether to throw deep or run the ball.  The Bills only have 4 sacks so far this year and they are going to have a hard time containing Vick in the pocket.  The Eagles are averaging 163.5 yards rushing per game and 5.4 yards per carry so far this year, so look for Lesean McCoy to also get the rock a lot in this game.  The Eagles like to throw the ball deep to the WRs, so the Bills will need to have the safeties give the corners a lot of help over the top in this game.

PREDICTION:  EAGLES 33, BILLS 24

The Buffalo Bills have rolled up 37.7 points and 431.0 yards of offense per game so far this year, which is amazing.  But, the Bengals are a solid defensive team allowing only 18.0 points and 276.3 yards per game (3rd best in the league).  Here is a look at the matchups in this game:

When the Bills have the ball:  The Bills have been incredible so far this year offensively.  They are likely going to try to be a little more balanced offensively to try to keep the Bengals’ solid defense honest.  That means that Fred Jackson is going to get the ball a lot both in the running game and out of the backfield in the passing game.  The Bengals are only giving up 88.0 yards rushing per game and 2.9 yards per carry, so Jackson is going to have to fight for every yard he gets.  The Bengals’ coaching staff knows Ryan Fitzpatrick better than any of the Bills’ opponents this year as he used to play for them.  The Bengals already have 9 sacks this year while the Bills have only given up 2 of them, so something has to give in this game.  The Bills will want to move the ball around and use everyone in the passing game, so that they can make the Bengals’ pay if they try to double cover Steve Johnson.  That means that David Nelson, Donald Jones and Scott Chandler are going to have to step up this weekend.

When the Bengals have the ball:  The Bengals are likely going to come out trying to pound the ball at the Bills’ D with Cedric Benson.  Benson is a very physical runner who gets stronger as the game goes on.  The Bills are giving up 115.7 yards rushing per game and 4.7 yards per carry, so the Bengals are likely going to try to run the ball at least 30 times in this game.  The Bills only have 2 sacks so far this year, so if they can’t get any pressure on Andy Dalton, he might have success throwing against them.  He likes throwing the ball down the field to his WRs (A.J. Green and Jerome Simpson), but that doesn’t mean that he won’t throw to his TE Jermaine Gresham and Andre Caldwell on the short stuff.

PREDICTION:  BILLS 21, BENGALS 20

The Buffalo Bills are going to show whether they are legit contenders or if their fast start is a mirage this weekend at home against the New England Patriots.  The Patriots have beaten the Bills 15 straight times including a 34-3 beatdown in Buffalo last year.  The Patriots outscored the Bills 72-33 last year.  Here is a look at the matchups this Sunday against the Patriots:

When the Bills have the football:  The Buffalo Bills are rushing for 190.0 yards rushing per game and 5.9 yards per carry so far this year.  Giving the ball to RBs Fred Jackson and C.J. Spiller is going to be the best gameplan for this weekend’s game against the Patriots.  The Bills need to control the clock and keep their defense off the field.  Ryan Fitzpatrick is off to a great start this year but he had issues against the Patriots last year as he only had 2 TD passes and 5 INTs against them.  The Patriots are giving up 381.0 yards passing per game this year, so if Fitzpatrick has time to throw the ball (he has only been sacked 1 time so far this year), he should have better success than last year.  The Patriots are likely going to double Steve Johnson and force Fitzpatrick to beat them by throwing to David Nelson and TE Scott Chandler.

When the Patriots have the ball:  The Patriots rushed for 417 yards (208.5 avg) against the Bills last year, so look for BenJarvus Green-Ellis and Danny Woodhead to get their fair share of carries this weekend.  The Bills are giving up 119.5 yards rushing and 5.0 yards per carry this year, so the front seven is going to have to step up.  The Bills only have 2 sacks this year and Tom Brady has already thrown for 940 yards, which is a recipe for disaster.  The Bills are going to have to blitz the OLBs in an attempt to get to Brady before he gets the ball off.  That is playing with fire though due to the fact that Brady gets rid of the ball so quick to Deion Branch, Rob Gronkowski, Wes Welker and Danny Woodhead out of the backfield.

PREDICTION:  PATRIOTS 37, BILLS 20

The Buffalo Bills stunned the NFL last weekend by kicking the Chiefs butts 41-7 on the road.  Now the Bills will face the Oakland Raiders in the home opener this weekend.  The Bills are going to have to tighten up the chinstraps this weekend as this is going to be a physical game.  Here is a look at the matchups in this game:

When the Bills have the ball:  The Bills are likely to be very balanced offensively in this game.  In fact, don’t be surprised to see the Bills throwing the ball a lot early in this game to try to build a lead and force the Raiders out of their running game.  The offensive line is going to have to keep Ryan Fitzpatrick clean just like last week when he was only sacked 1 time.  Fitzpatrick is going to look Stevie Johnson’s way a lot in this game, but he will likely be double covered a lot.  So, the Bills are going to need TE Scott Chandler, WR David  Nelson and WR Donald Jones to step up and make some plays.  The Raiders only gave up 38 yards rushing on 13 carries (2.9 ypc) last Monday Night against the Broncos, so Fred Jackson is going to have to fight for every yard he gets this weekend.

When the Raiders have the ball:  The front seven of the Bills is going to be challenged this weekend, as they Raiders rushed for 190 yards on 39 carries (4.9 ypc) last weekend against the Broncos.  The Bills gave up 108 yards rushing on 18 carries (6.0 ypc) against the Chiefs last weekend, so this could get ugly.  Darren McFadden is a true breakaway threat while Michael Bush brings the power in the running game for the Raiders.  The Raiders like to throw the ball deep off of playaction, so the Bills are going to have to get to Jason Campbell.

PREDICTION:  RAIDERS 20, BILLS 17

The Buffalo Bills better hope they fixed up the run defense in the off-season because they will have to deal with the Chiefs’ running game on Sunday, and they led the NFL in rushing last year.  Also, Arrowhead Stadium is one of the loudest in the NFL, so the Bills will need to move the ball and score early in this game to quiet the crowd.  Here is a look at the matchups in this game:

When the Bills have the ball:  The Bills are likely going to try to run the ball much more than usual in this game in an attempt to control the clock and keep the defense off the field at the same time.  Fred Jackson will be the main ball carrier for the Bills, but look for C.J. Spiller and Brad Smith to also get in on the action this Sunday.  The offensive line is going to have to keep OLB Tamba Hali and DEs Tyson Jackson and Glenn Dorsey out of the backfield if Ryan Fitzpatrick is going to have any success throwing the ball.  Steve Johnson is going to likely be double covered most of the game by the Chiefs.  That means that the Bills are going to need Donald Jones, Roscoe Parrish, Brad Smith and starting TE Scott Chandler to step up on Sunday.

When the Chiefs have the ball:  The Bills have to sell out to stop Jamaal Charles and Thomas Jones.  If those guys get going, it’s going to be a long day for the Bills’ D.  The Bills hope that Marcell Dareus and Nick Barnett step up in their debuts on Sunday.  The Bills are going to turn OLBs Shawne Merriman and Chris Kelsay loose on passing downs as they will try to hunt down Chiefs’ QB Matt Cassel.  Cassel cracked a rib in the Chiefs’ last preseason game and the Chiefs only have Tyler Palko and Ricky Stanzi behind him on the roster.  The Bills’ safeties should be able to cheat on coverage a little bit because TE Leonard Pope isn’t much of a threat in the passing game.  That’s good news because the CBs will probably need help with Dwayne Bowe, as he is a big WR.

PREDICTION:  CHIEFS 20, BILLS 14

The Bills got crushed 34-3 by the Patriots last weekend but they have won 4 of their last 7 games after starting the year 0-8.  They got drilled 38-14 by the Jets in Buffalo earlier this year.  The good news is that the Jets will likely be resting some of their key players tomorrow.  The bad news is that Ryan Fitzpatrick’s knee is really bothering him which could cause him to miss tomorrow’s game.  The Jets have lost three of their last four games as they are limping into the playoffs.  Here is a look at the matchups in this game:

When the Bills have the ball:  No matter who plays QB tomorrow, the Bills want to try to get RB Fred Jackson to 1,000 yards rushing.  To do that he’s going to need at least 108 yards rushing tomorrow.  That would usually be tough against the Jets who are allowing 94.5 yards rushing per game and 3.6 yards per carry but with them resting their starters he might just get there.  If the Bills can protect Ryan Fitzpatrick or Brian Brohm, they should be able to make some plays down the field.  I have a feeling that the Bills are going to use C.J. Spiller as a wideout some tomorrow due to all of the injuries the Bills have suffered there.  The Jets will be playing close attention to Steve Johnson in this game as he is without a doubt the best WR on the Bills.

When the Jets have the ball:  Mark Sanchez might make a token start tomorrow but I don’t look for him to play much with his shoulder barking as it just doesn’t make any sense to play him.  Crusty old vet, Mark Brunell will likely get the bulk of the P.T. under center and he’s running on fumes.  I have a feeling that Brad Smith and rookie RB Joe McKnight are going to be the top WR and RB for the Jets tomorrow.

PREDICTION:  BILLS 20, JETS 17

The Buffalo Bills have won two games in a row and 4 of their last 6 games so they are feeling good about themselves right now.  They also played well in the first game between these two teams losing only 38-30 to them inn Foxboro.  The Patriots have the best record in the AFC and they have won six games in a row so they are coming into this game red hot!  Here is a look at the matchups in this game:

When the Bills have the ball:  The Bills are going to likely be balanced in this game as they don’t want to get into an all-out scoring war.  Fred Jackson, C.J. Spiller and QB Ryan Fitzpatrick are likely all going to take some shots at a Patriots’ D that is giving up 111.4 yards rushing and 4.2 yards per carry.  The Patriots are not much of a pass rushing team so Fitzpatrick is going to have time to throw the ball.  He will need his young receivers (Steve Johnson, David Nelson and Donald Jones) to make some plays down the field.

When the Patriots have the ball:  BenJarvus Green-Ellis & Danny Woodhead are likely going to be a big part of the Patriots’ offense in this game so the Bills’ front seven will have to step up.  The Bills must also get a pass rush on Tom Brady because if he has time to throw the ball he’s going to torch the Bills’ secondary.  I think it would be a good idea for the Bills’ corners to play bump and run to try to screw up Brady’s timing with his WRs.

PREDICTION:  PATRIOTS 34, BILLS 27

The Bills won last weekend against the Browns 13-6 and they are 3-5 since their bye week as they have played pretty well lately.  The Bills lost 15-10 in the season opener at home against the Dolphins and the Fins are a much better road than home team….giving the Bills hope this weekend.  The Dolphins have alternated wins and losses the last 10 weeks and they beat the Jets 10-6 last weekend.  Here is a look at the matchups in this game:

When the Bills have the ball:  The Bills are likely going to mix things up on offense.  Fred Jackson & C.J. Spiller will have to fight for every yard they get against a Dolphins’ D that is only allowing 3.6 yards per carry this year.  The Bills must be able to keep Cameron Wake (14 sacks) away from Ryan Fitzpatrick if they want him to have any chance of making plays against a Fins’ D that is allowing 200.6 yards passing per game this year.  David Nelson will likely enter the starting lineup in Lee Evans’ spot and the Bills will need him to produce so the Fins don’t double Steve Johnson all the time.

When the Dolphins have the ball:  The Dolphins are going to run the ball a lot this Sunday.  The Bills are giving up 165.8 yards rushing per game and 4.7 yards per carry so far this year so Ronnie Brown & Ricky Williams could both have big games this Sunday.  The Dolphins better hope they get a running game going because Chad Henne has been awful lately and the Bills’ secondary has been playing better as of late.

PREDICTION:  DOLPHINS 20, BILLS 17

The Buffalo Bills have lost two games in a row after coming off back to back wins over the Lions & Bengals.  The Browns have won 2 games in a row and 4 of their last six games.  The weather is likely to be awful this Sunday and with that in mind, here is a look at the matchups in this game:

When the Bills have the ball:  The Bills are likely going to build the offensive gameplan around Fred Jackson and C.J. Spiller both running the ball and catching balls out of the backfield.  The Browns are giving up 119.1 yards rushing per game and 4.1 yards per carry so far this year.  Ryan Fitzpatrick will also likely use his feet in this game as the Browns have had trouble with QBs taking off running out of the pocket.  Fitzpatrick is going to have a hard time getting the ball to his receivers due to the weather and the fact that the Browns’ secondary has been incredible lately as they have 18 INTs this year.

When the Browns have the ball:  The Bills’ D is going to have to tighten up the chinstraps this weekend as Peyton Hillis will take aim at them seeing how they are giving up 170.9 yards rushing per game and 4.7 yards per carry.  The Bills have allowed opposing teams to rush for over 200 yards six times this year!   The Bills will also have to deal with TE Ben Watson who has had some huge games against the Bills including a 2-TD game in his last meeting with them.

PREDICTION:  BROWNS 17, BILLS 13